عنوان انگلیسی مقاله:
Indications and classes of outpatient antibiotic prescriptions in Japan: A descriptive study using the national database of electronic health insurance claims, 2012–2015
ترجمه فارسی عنوان مقاله:
نشانه ها و کلاسهای تجویز آنتی بیوتیک سرپایی در ژاپن: یک مطالعه توصیفی با استفاده از بانک اطلاعاتی ملی ادعاهای بیمه الکترونیکی بهداشت ، 2012-2015
Sciencedirect - Elsevier - International Journal of Infectious Diseases, 91 (2020) 1-8: doi:10:1016/j:ijid:2019:11:009
Hideki Hashimotoa,b, Makoto Saitoc, Jumpei Satod, Kazuo Godad, Naohiro Mitsutakee, Masaru Kitsuregawad, Ryozo Nagaif, Shuji Hatakeyamaa
Objectives: To evaluate condition-specific antibiotic prescription rates and the appropriateness of
antibiotic use in outpatient settings in Japan.
Methods: Using Japan’s national administrative claims database, all outpatient visits with infectious disease
diagnoses were linked to reimbursed oral antibiotic prescriptions. Prescription rates stratified by age, sex,
prefecture, and antibiotic category were determined for each infectious disease diagnosis. The proportions
of any antibiotic prescription to all infectious disease visits and the proportions of
prescriptions to all antibiotic prescriptions were calculated for each infectious disease diagnosis.
Results: Of the 659 million infectious disease visits between April 2012 and March 2015, antibiotics were
prescribed in 266 million visits (704 prescriptions per 1000 population per year). Third-generation
cephalosporins, macrolides,and quinolonesaccountedfor 85.9%ofall antibiotic prescriptions.Fifty-sixpercent
diagnoses with frequent antibiotic prescription were bronchitis (184 prescriptions per 1000 population per
year), viral upper respiratory infections (166), pharyngitis (104), sinusitis (52), and gastrointestinal infection
(41), for which 58.3%, 40.6%, 58.9%, 53.9%,and 26.1% of visits antibiotics were prescribed, respectively. First-line
antibiotics were rarely prescribed for pharyngitis (8.8%) and sinusitis (9.8%). More antibiotics were prescribed
for children aged 0–9 years, adult women, and patients living in western Japan.
Conclusions: Antibiotic prescription rates are high in Japan. Acute respiratory or gastrointestinal infections,
which received the majority of the antibiotics generally not indicated, should be the main targets of
antimicrobial stewardship intervention.
Keywords: National administrative claims database | Big data | Antibiotic | Antimicrobial stewardship