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عنوان انگلیسی مقاله:
Evaluating the knowledge, attitudes and practices of healthcare workers towards adverse drug reaction reporting at a public tertiary hospital in Johannesburg
ترجمه فارسی عنوان مقاله:
ارزیابی دانش ، نگرش و عملکرد کارکنان بهداشت و درمان نسبت به گزارش عوارض جانبی داروی مضر در یک بیمارستان عمومی دولتی جوهانسبورگ
Sciencedirect - Elsevier - International Journal of Africa Nursing Sciences, 12 (2020) 100191. doi:10.1016/j.ijans.2020.100191
Yashmay Gordhon⁎, Neelaveni Padayachee
Background: Spontaneous reporting of adverse drug reactions is a method of monitoring the safety of drugs postmarketing,
providing a way to discover new, rare or unnoticed adverse drug reactions. Despite its importance,
there is widespread underreporting of adverse drug reactions by health care professionals in South Africa. The
study assessed the knowledge, attitudes and practices of health care professionals on adverse drug reaction
reporting at a tertiary public-sector hospital in Johannesburg, South Africa.
Methods: A descriptive quantitative study using a questionnaire was conducted at a tertiary public-sector hospital
in Johannesburg. A stratified sampling method was used to distribute questionnaires to doctors, nurses and
pharmacists at the institution from July to November 2016.
Results: Of the 338 questionnaires sent out, 297 health care professionals responded to the questionnaire
(87.87% response rate). Half of the participants knew about reporting adverse drug reactions, and pharmacists
were the most likely group to know how to report (82.61%) (p < 0.001). Ninety-seven percent of participants
who had previously received adverse drug reaction training knew how to report them. Patient management, lack
of knowledge and the time-consuming requirement of reporting featured as discouraging factors. Although,
58.59% of participants had encountered adverse drug reactions, only 16.50% had reported (p < 0.001).
Conclusions: Despite an awareness of adverse drug reactions, participants were unlikely to report adverse drug
reactions due to time constraints and a lack of knowledge. Adverse drug reaction reporting is essential to ensuring
patient safety. The benefits of reporting should be emphasized by encouraging continuous professional
development in pharmacovigilance and, placing more emphasis on adverse drug reactions at an undergraduate
Keywords: Pharmacovigilance | Adverse drug reaction reporting | Medicine safety | Healthcare professionals