دانلود مقاله انگلیسی رایگان:یادگیری تقویتی احتمالی نابجا در بستگان درجه یک افراد مبتلا به اختلال دو قطبی - 2020
دانلود بهترین مقالات isi همراه با ترجمه فارسی
دانلود مقاله انگلیسی یادگیری تقویتی رایگان
  • Aberrant probabilistic reinforcement learning in first-degree relatives of individuals with bipolar disorder Aberrant probabilistic reinforcement learning in first-degree relatives of individuals with bipolar disorder
    Aberrant probabilistic reinforcement learning in first-degree relatives of individuals with bipolar disorder

    سال انتشار:

    2020


    عنوان انگلیسی مقاله:

    Aberrant probabilistic reinforcement learning in first-degree relatives of individuals with bipolar disorder


    ترجمه فارسی عنوان مقاله:

    یادگیری تقویتی احتمالی نابجا در بستگان درجه یک افراد مبتلا به اختلال دو قطبی


    منبع:

    Sciencedirect - Elsevier - Journal of Affective Disorders, 264 (2020) 400-406. doi:10.1016/j.jad.2019.11.063


    نویسنده:

    Julia O. Linkea,⁎, Georgia Koppeb, Vanessa Scholza, Philipp Kanskec,d, Daniel Durstewitzb, Michèle Wessaa


    چکیده انگلیسی:

    Background: Motivational dysregulation represents a core vulnerability factor for bipolar disorder. Whether this also comprises aberrant learning of stimulus-reinforcer contingencies is less clear. Methods: To answer this question, we compared healthy first-degree relatives of individuals with bipolar disorder (n = 42) known to convey an increased risk of developing a bipolar spectrum disorder and healthy individuals (n = 97). Further, we investigated the effects of the behavioral activation system (BAS) on reinforcement learning across the entire sample. All participants were assessed with a probabilistic learning task that distinguishes learning from positive and negative feedback. Main outcome measures included choice frequencies and learning rate parameters generated by computational reinforcement learning algorithms. Results: First-degree relatives choose more rewarding stimuli more consistently and showed marginally reduced learning rates from unexpected negative feedback. Further, first-degree relatives had lower BAS scores than controls, which were negatively associated with learning rates from unexpected negative feedback. Limitations: However as probands also reported other mental disorders such as Attention-Deficit/Hyperactivity Disorder and substance abuse among their first-degree relatives, we cannot know, whether these findings are specific to the risk for bipolar disorder. Conclusion: The behavior of first-degree relatives of individuals with bipolar disorder, who also display increased BAS sensitivity, is less influenced by unexpected negative feedback. This reduced learning from unexpected negative feedback biases subsequent choices towards stimuli with higher probabilities for a reward. In sum, our results confirm the role of aberrant reinforcement learning in the pathophysiology of bipolar disorder.
    Keywords: Bipolar disorder | First-degree relatives | Behavioral activation system (BAS) | Reinforcement learning | Computational modeling


    سطح: متوسط
    تعداد صفحات فایل pdf انگلیسی: 7
    حجم فایل: 544 کیلوبایت

    قیمت: رایگان


    توضیحات اضافی:




اگر این مقاله را پسندیدید آن را در شبکه های اجتماعی به اشتراک بگذارید (برای به اشتراک گذاری بر روی ایکن های زیر کلیک کنید)

تعداد نظرات : 0

الزامی
الزامی
الزامی
rss مقالات ترجمه شده rss مقالات انگلیسی rss کتاب های انگلیسی rss مقالات آموزشی
logo-samandehi