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دسته بندی:
برق الکترونیک - Power Electronics
سال انتشار:
2021
عنوان انگلیسی مقاله:
Electro-conductive carbon nanofibers containing ferrous sulfate for bone tissue engineering
ترجمه فارسی عنوان مقاله:
Electro-conductive carbon nanofibers containing ferrous sulfate for bone tissue engineering
منبع:
ScienceDirect- Elsevier- Life Sciences, 282 (2021) 119602: doi:10:1016/j:lfs:2021:119602
نویسنده:
Houra Nekounam
چکیده انگلیسی:
The application of electroactive scaffolds can be promising for bone tissue engineering applications. In the
current paper, we aimed to fabricate an electro-conductive scaffold based on carbon nanofibers (CNFs) containing ferrous sulfate. FeSO4⋅7H2O salt with different concentrations 5, 10, and 15 wt%, were blended with
polyacrylonitrile (PAN) polymer as the precursor and converted to Fe2O3/CNFs nanocomposite by electrospinning and heat treatment. The characterization was conducted using SEM, EDX, XRD, FTIR, and Raman
methods. The results showed that the incorporation of Fe salt induces no adverse effect on the nanofibers
morphology. EDX analysis confirmed that the Fe ions are uniformly dispersed throughout the CNF mat. FTIR
spectroscopy showed the interaction of Fe salt with PAN polymer. Raman spectroscopy showed that the incorporation of FeSO4⋅7H2O reduced the ID/IG ratio, indicating more ordered carbon in the synthesized nanocomposite. Electrical resistance measurement depicted that, although the incorporation of ferrous sulfate
reduced the electrical conductivity, the conductive is suitable for electrical stimulation. The in vitro studies
revealed that the prepared nanocomposites were cytocompatible and only negligible toxicity (less than 10%)
induced by CNFs/Fe2O3 fabricated from PAN FeSO4⋅7H2O 15%. Although various nanofibrous composite
fabricated with Fe NPs have been evaluated for tissue engineering applications, CNFs exhibited promising
properties, such as excellent mechanical strength, biocompatibility, and electrical conductivity. These results
showed that the fabricated nanocomposites could be applied as the bone tissue engineering scaffold.
Keywords: Bone tissue engineering | Electrospinning | Carbon nanofiber | Ferrous sulfate
قیمت: رایگان
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