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ردیف | عنوان | نوع |
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1 |
Astrocyte-induced intermittent synchronization of neurons in a minimal network
هماهنگ سازی متناوب نورون ها در یک شبکه کمینه با آستروسیت ها-2020 We investigate the impact of mixed coupling on synchronization in a minimal multiplex neuro-astrocytal ensemble, inspired by physiological systems. We find that calcium activity in astrocytes can effectively mediate neural interactions and control cooperative dynamics of neurons. In particular, astrocytes can in- duce the intermittent synchronization of a pair synaptically coupled fast spiking Hodgkin-Huxley neurons on the slow timescale of calcium oscillations. Keywords: Synchronization | Multiple timescales | Neuron-astrocyte network | Hodgkin-Huxley neuron | Ullah-Jung astrocyte |
مقاله انگلیسی |
2 |
Hyperexcitable Neurons Enable Precise and Persistent Information Encoding in the Superficial Retrosplenial Cortex
نورون های Hiperexciable رمزگذاری اطلاعات دقیق و مداوم در قشر Retrosplenial سطحی-2020 The retrosplenial cortex (RSC) is essential for memory
and navigation, but the neural codes underlying
these functions remain largely unknown. Here, we
show that the most prominent cell type in layers 2/3
(L2/3) of the mouse granular RSC is a hyperexcitable,
small pyramidal cell. These cells have a low rheobase
(LR), high input resistance, lack of spike frequency
adaptation, and spike widths intermediate to those
of neighboring fast-spiking (FS) inhibitory neurons
and regular-spiking (RS) excitatory neurons. LR cells
are excitatory but rarely synapse onto neighboring
neurons. Instead, L2/3 is a feedforward, not feedback,
inhibition-dominated network with dense
connectivity between FS cells and from FS to LR neurons.
Biophysical models of LR but not RS cells precisely
and continuously encode sustained input from
afferent postsubicular head-direction cells. Thus, the
distinct intrinsic properties of LR neurons can support
both the precision and persistence necessary
to encode information over multiple timescales in
the RSC. |
مقاله انگلیسی |