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نتیجه جستجو - encapsulation

تعداد مقالات یافته شده: 12
ردیف عنوان نوع
1 Encapsulation of olive leaf phenolics within electrosprayed whey protein nanoparticles; production and characterization
محصور کردن فنل های برگ زیتون در نانوذرات پروتئین آب پنیر با الکتروپراس; تولید و توصیف-2020
Nanoencapsulation is an emerging research field in different disciplines including food, pharmaceutical, and cosmetic industries. In this work, nanoparticles containing olive leaf extract (OLE) were prepared from whey protein concentrate (WPC) via electrospraying and the impact of core and wall concentration on the morphology, encapsulation efficiency, zeta potential, particle size, and polydispersity index (PDI) of capsules was studied. Also, chemical structure and phenolic profile of final nanocarriers was analyzed by Fourier-transform infrared spectroscopy (FTIR), and high performance liquid chromatography (HPLC), respectively. Our results showed that spherical nanoparticles were obtained through electrospraying and their size was dependent on applied levels of WPC and OLE. Encapsulation efficiency increased significantly (P < 0.05) at higher contents of OLE and WPC. All produced particles had a negative zeta potential. FTIR data revealed no new spectrum in the encapsulated samples and only a new peak (at 611.23 cm???? 1) was observed for 15% WPC particles containing 1000 ppm phenolics. The mean size of electrosprayed WPC nanoparticles was 232.3–659.8 nm with a PDI of 0.074–0.650, revealing a heterogeneous nanoparticle population. By increasing WPC (from 15% to 30%), smaller particles were observed with higher encapsulation efficiencies. Also, increasing the OLE (from 500 to 1000 ppm) resulted in bigger particles. HPLC analysis showed that nanocarriers of 15% WPC loaded with 500 ppm phenolics had the highest content of oleuropein (138 mg/kg), tyrosol (42 mg/kg) and caffeic acid (36 mg/kg); but the highest level of hydroxytyrosol (94 mg/kg) was found in particles with a composition of 15% WPC and 1000 ppm phenolics.
Keywords: Electrospraying | Nanoencapsulation | Phenolic compounds | Whey proteins | Nanocarriers
مقاله انگلیسی
2 Review on performance assessment of phase change materials in buildings for thermal management through passive approach
مروری بر ارزیابی عملکرد مواد تغییر فاز در ساختمانها برای مدیریت حرارتی از طریق رویکرد غیرفعال-2020
Latent heat energy storage (LHES) systems using phase change materials (PCMs) are well known for its excellent thermal energy storage and release during melting and solidifications respectively. PCMs can be efficiently deployed in applications where significant temperature difference exists in the system for intermittent thermal energy storage. Several research contributions has been made on integrating PCMs in buildings for thermal management, as it enhances building thermal inertia, reduces maximum heat flux, shifts peak energy demand, reduces temperature fluctuations of air, etc., owing to its isothermal behavior and high energy storage density during phase change. Results of several research articles reveal that incorporation of PCM in buildings could significantly improve indoor comfort conditions and reduce energy demand of Heating ventilation and air conditioning (HVAC) systems, provided appropriate PCM selection, encapsulation methods, location deployed etc. This review paper is devoted to elucidate various facts attributing PCM integration in buildings for thermal management through passive approach. The facts includes performance of PCMs in buildings in terms of heat gain reduction, temperature attenuation, peak energy demand shifting and energy saving potential, encapsulation deployed, are discussed and presented in order to expedite the interpretation for future researchers, who took their research work in the field of building thermal energy management.
Keywords: Phase change material | Passive approach | Thermal energy management | PCM Encapsulation | Buildings
مقاله انگلیسی
3 Shape-stable thermo-responsive nano Fe3O4/fatty acids/PET composite phase-change material for thermal energy management and saving applications
شکل دهی به پایدار نانو Fe3O4 با پاسخگویی حرارتی / اسیدهای چرب / مواد تغییر فاز کامپوزیت PET برای مدیریت انرژی حرارتی و صرفه جویی در برنامه های کاربردی-2020
Organic phase change materials are sensitive to temperature calling thermo-responsive materials having ability of thermal energy storage/release in a warm/cold medium through latent heat, indicating proper potential for better thermal energy management. Nonetheless, leakage during melting and undesirable thermal conductivity are considered as two major disadvantages. Herein, for the first time, a simple one-step route is suggested for preparing novel shape-stable nano Fe3O4/fatty acids/PET composite can be utilized in thermal energy saving and management applications. This is based on simultaneous embedment of fatty acids as phase change materials into polyester (PET) fibers as supporting material and formation of iron oxide nanoparticles. The present approach not only obviates two stated drawbacks but also it is free from separately forming or providing nanoparticles and utilizing micro/nano encapsulation or electrospinning which may contain toxic chemicals. It is further conducted in one-single step preferring in the view of both economic and environmental aspects. The composites indicated promising phase temperature intervals of 36.3–54.1 and 26.9–35.5 °C for melting and freezing with latent heats of 40.3–59.7 and 40.1–58.2 J/g, respectively. The embedment of iron oxide nanoparticles resulted in thermal conductivity elevation around 44.5–85.8%. The prepared samples displayed good thermal endurance and reliability after 100 thermal treatments. They also had no leakage even after 120 min at 75 °C revealed their appropriate leakage-proof property in real usages. Overall, the paper introduces an affordable one-step mode for fabricating shape-stable nano-enhanced composite with proper thermal features for practical thermal energy management and saving applications.
Keywords: Phase change materials | Thermal conductivity | Thermal management and storage | Fatty acid | Iron oxide nanoparticles
مقاله انگلیسی
4 Combined heat and power system intelligent economic dispatch: A deep reinforcement learning approach
توزیع اقتصادی سیستم گرمایشی و هوشمند: یک رویکرد یادگیری تقویتی عمیق-2020
This paper proposed a Deep Reinforcement learning (DRL) approach for Combined Heat and Power (CHP) system economic dispatch which obtain adaptability for different operating scenarios and significantly decrease the computational complexity without affecting accuracy. In the respect of problem description, a vast of Combined Heat and Power (CHP) economic dispatch problems are modeled as a high-dimensional and nonsmooth objective function with a large number of non-linear constraints for which powerful optimization algorithms and considerable time are required to solve it. In order to reduce the solution time, most engineering applications choose to linearize the optimization target and devices model. To avoid complicated linearization process, this paper models CHP economic dispatch problems as Markov Decision Process (MDP) that making the model highly encapsulated to preserve the input and output characteristics of various devices. Furthermore, we improve an advanced deep reinforcement learning algorithm: distributed proximal policy optimization (DPPO), to make it applicable to CHP economic dispatch problem. Based on this algorithm, the agent will be trained to explore optimal dispatch strategies for different operation scenarios and respond to system emergencies efficiently. In the utility phase, the trained agent will generate optimal control strategy in real time based on current system state. Compared with existing optimization methods, advantages of DRL methods are mainly reflected in the following three aspects: 1) Adaptability: under the premise of the same network topology, the trained agent can handle the economic scheduling problem in various operating scenarios without recalculation. 2) High encapsulation: The user only needs to input the operating state to get the control strategy, while the optimization algorithm needs to re-write the constraints and other formulas for different situations. 3) Time scale flexibility: It can be applied to both the day-ahead optimized scheduling and the real-time control. The proposed method is applied to two test system with different characteristics. The results demonstrate that the DRL method could handle with varieties of operating situations while get better optimization performance than most of other algorithms.
Keywords: Combined heat and power economic dispatch | Deep reinforcement learning | Proximal policy optimization
مقاله انگلیسی
5 ساختار یک قفس پروتئینی باکتریایی قوی و کاربرد آن به‌عنوان یک پلت فرم بیوکاتالیستی همه‌کاره از طریق کپسوله سازی آنزیم
سال انتشار: 2020 - تعداد صفحات فایل pdf انگلیسی: 6 - تعداد صفحات فایل doc فارسی: 17
با استفاده از یک انکاپسولین تازه کشف‌شده از Mycolicibacterium hassiacum ، چندین بیوکاتالیست در این قفس پروتئینی قوی بسته‌بندی شدند. مشخص شد که تولید انکاپسولین به‌عنوان پروتئین نوترکیب آسان است. با روشن شدن ساختار کریستالی آن مشخص شد که این یک قفس پروتئینی کروی 60 پروترومری (قطر 23 نانومتر) با منافذ باریک است. با ایجاد یک روش بیان همزمان و جداسازی مؤثر، می‌توان اثر بسته‌بندی انواع بیوکاتالیست ها را ارزیابی کرد. نشان داده شد که نتایج کپسول سازی در ثبات بسیار بالاتری از بیوکاتالیست ها وجود دارد. بیشتر بیوکاتالیست¬های حاوی کوفاکتورهای هدف‌دار در انکاپسولین فعال باقی مانده‌اند. به دلیل محدود بودن قطرهای منافذ انکاپسولین (9-5 آنگستروم)، قفس پروتئین از آنزیم‌های کپسوله شده در برابر ترکیبات حجیم محافظت می‌کند. این کار تحقیقاتی نشان می‌دهد که انکاپسولین¬ها ممکن است ابزار ارزشمندی برای تنظیم خواص بیوکاتالیست ها مانند ثبات و ویژگی بستر باشد.
کلیدواژه‌ها: کپسوله سازی | ساختار کریستالی | پایداری آنزیم | تجزیه‌وتحلیل زیستی | کوفاکتور
مقاله ترجمه شده
6 Immune recognition, antimicrobial and opsonic activities mediated by a sialic acid binding lectin from Ruditapes philippinarum
تشخیص ایمنی ، فعالیت ضد میکروبی و اپسونیک به واسطه یک لکتین اتصال اسید سیالیک از Ruditapes philippinarum-2019
In the present study, a sialic acid-binding lectin was identified and characterized from Manila clam Ruditapes philippinarum (designed as RpSABL-1). Multiple alignments strongly suggested that RpSABL-1 was a new member of the sialic acid-binding lectin family. In non-stimulated clams, RpSABL-1 transcripts were constitutively expressed in all five tested tissues, especially in hepatopancreas. After Vibrio anguillarum challenge, the expression of RpSABL-1 mRNA was significantly up-regulated at 6 h (P < 0.05), 12 h (P < 0.01) and 24 h (P < 0.01). Recombinant RpSABL-1 protein (rRpSABL-1) displayed apparent binding activities towards lipopolysaccharides (LPS) and peptidoglycan (PGN), but not to glucan or chitin in vitro. Coinciding with the PAMPs binding assay, rRpSABL-1 exhibited obvious agglutination activities against Gram-positive bacterium Staphyloccocus aureus, Gram-negative bacteria Escherichia coli, V. anguillarum and Vibrio harveyi. Meanwhile, rRpSABL-1 showed antibacterial activities against E. coli, and biofilm formation of E. coli could also be inhibited after incubated with rRpSABL-1. Moreover, the encapsulation, phagocytosis and chemotactic ability of hemocytes could be enhanced by rRpSABL-1. All these results suggested that RpSABL-1 could function as a pattern recognition receptor with versatile functions in the innate immune responses of R. philippinarum.
Keywords: Ruditapes philippinarum | Sialic acid-binding lectin | Pattern recognition receptor | Immune recognition
مقاله انگلیسی
7 A sialic acid-binding lectin with bactericidal and opsonic activities from Ruditapes philippinarum
لکتین با اسید سیالیک با فعالیتهای ضد باکتری و اپسونیک از Ruditapes Philippinarum-2019
In the present study, a sialic acid-binding lectin was cloned and characterized from Manila clam Ruditapes philippinarum (designed as RpSabl). The open reading frame of RpSabl encoded a polypeptide of 162 amino acids with a calculated molecular mass of 17.7 kDa. Analysis of the conserved domain suggested that RpSabl was a new member of the sialic acid-binding lectins family. In non-stimulated clams, RpSabl transcripts were constitutively expressed in all five tested tissues, especially in hepatopancreas. After Vibrio anguillarum challenge, the expression of RpSabl mRNA in hepatopancreas was significantly up-regulated at 3 h (3.8-fold, P < 0.05), 6 h (4.9-fold, P < 0.05), 12 h (12.3-fold, P < 0.01) and 24 h (9.7-fold, P < 0.01), while RpSabl transcripts in hemocytes was only significantly up-regulated at 6 h (8.5-Fold, P < 0.01). RNAi-mediated knockdown of RpSabl transcripts affected the survival rates of Manila clam against V. anguillarum, perhaps mainly due to the inhibited expression of antibacterial effectors (e.g. lysozyme and defensin). Moreover, recombinant protein of RpSabl (rRpSabl) possessed binding activities towards lipopolysaccharides (LPS), peptidoglycan (PGN) and glucan in vitro. Coinciding with the Pathogen-associated molecular patterns (PAMPs) binding assay, rRpSabl displayed broad bacterial-agglutination properties towards Vibrio harveyi, Vibrio splendidus, V. anguillarum, Enterobacter cloacae and Aeromonas hydrophila. Meanwhile, the phagocytosis and encapsulation ability of hemocytes could be significantly enhanced by rRpSabl incubation. All these results showed that RpSabl could function as a versatile molecule involved in the innate immune responses of R. philippinarum.
Keywords: Ruditapes philippinarum | Sialic acid-binding lectin | Pattern recognition receptor | Immune recognition
مقاله انگلیسی
8 Practical considerations for the encapsulation of multi-enzyme cargos within the bacterial microcompartment for metabolic engineering
ملاحظات عملی برای کپسوله سازی محموله چند آنزیمی در microcompartment باکتریایی برای مهندسی متابولیک-2017
Subcellular organization, the sequestration of enzymes and metabolites within a synthetic organelle, is an important emerging technology for the optimization of microbial hosts for industrial applications. The bacterial microcompartment (MCP) performs this sequestration function to enhance various native metabolic processes. The defining feature of the MCP is a protein shell surrounding a series of enzymes. To apply the MCP for metabolic engineering, efforts in the field are directed towards localizing enzymes within the MCP. There have been recent advances in the understanding of protein interactions involved in MCP assembly, the application of encapsulation mediating peptides to model cargos, and control over loading of such cargos. With these techniques, it is possible to encapsulate multi-enzyme cascades.
مقاله انگلیسی
9 توانایی نیکوتین در قرار دادن پیوگلیتازون در داخل نانولوله کربنی : بررسی با کمک دینامیک مولکولی وتئوری تابع چگالی
سال انتشار: 2016 - تعداد صفحات فایل pdf انگلیسی: 42 - تعداد صفحات فایل doc فارسی: 28
مقاله ترجمه شده
10 خواص ساختاری، انرژی و الکترونی از احاطه کردن داروی پنسیل امین بر روی نانولوله کربنی بر مبنی چشم اندازی از vdW-DF
سال انتشار: 2015 - تعداد صفحات فایل pdf انگلیسی: 8 - تعداد صفحات فایل doc فارسی: 18
اصل اول محاسبات تابع دانسیته واندروالس vdW-DF با استفاده از تابع GGA/PBE و تابع پایه DZP در بسته های SIESTA برای بررسی احاطه کردن داروی پنسیل امین بر روی نانولوله کربنی تک دیواره صندلی و زیگزاکی اجرا می شود. نتایج بدست امده نشان می دهد که اتصال دارو در اطراف نانولوله کربنی تک دیواره زیگزاکی SWCNT در مقایسه همراه با همتای صندلی خودش معروف تر است. ادرس در اینجا نقشی از برهمکنش vdW برای داروی پنسیل امین در زمان گنجاندن دارو در نانولوله کربنی است. لازم به ذکر است که احاطه کردن از نیروی vdW می تواند در خواص پیوندی موثر باشد. ساختار الکترونی و جمعیت بار مولیکن برای بررسی انرژی بیشتر کمپلکس های معروف انالیز می شود که نشان داده می شود که احاطه کردن پنسیل امین تغییرات ارامی در خواص الکترونیک از SWCNT دارد و بدیهی است انتقالات برای دارو با نانولوله در طی فرایند احاطه سازی بهتر است. توصیف مقدار فعالیت جهانی مانند الکترونگاتیویته X، سختی جهانی ، نرمی جهانی S، پتانسیل الکترو شیمیایی و شاخص الکترون خواهی محاسبه می شود. پیش بینی شده است که این یافته ها راه جدید و مقداری اطلاعات برای کمک در مطالعات ازمایشگاهی و کاربردهای اینده ایجاد می کند.
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