دانلود و نمایش مقالات مرتبط با mechanism::صفحه 1
بلافاصله پس از پرداخت دانلود کنید
نتیجه جستجو - mechanism

تعداد مقالات یافته شده: 1204
ردیف عنوان نوع
1 تکنیک ها و کاربردهای توالی یابی RNA تک سلولی در تحقیقات تکوین تخمدان و بیماری های مرتبط
سال انتشار: 2022 - تعداد صفحات فایل pdf انگلیسی: 7 - تعداد صفحات فایل doc فارسی: 23
تخمدان یک ارگان بسیار سازمان یافته متشکل از سلول های زایا و انواع مختلف سلول های سوماتیک است که ارتباطات آنها منجر به تکوین تخمدان و تولید تخمک های عملکردی می شود. تفاوت بین سلول های منفرد ممکن است اثرات عمیقی بر عملکرد تخمدان داشته باشد. تکنیک‌های توالی‌یابی RNA تک سلولی، رویکردهای امیدوارکننده‌ای برای کشف ترکیب انواع سلولی ارگانیسم ها، پویایی رونوشت‌ها یا ترنسکریپتوم، شبکه تنظیم‌کننده بین ژن‌ها و مسیرهای سیگنال‌دهی بین انواع سلول‌ها در وضوح تک سلولی هستند. در این مطالعه، ما یک مرور کلی از تکنیک‌های توالی‌یابی RNA تک سلولی موجود از جمله Smart-seq2 و Drop-seq و همچنین کاربردهای آن‌ها در تحقیقات بیولوژیکی و بالینی ارائه می‌کنیم تا درک بهتری از مکانیسم‌های مولکولی زیربنای تکوین تخمدان و بیماری های مرتبط با آن ارائه کنیم.
کلیدواژگان: تکوین تخمدانن | توالی یابی RNA تک سلولی | شبکه تنظیمی | بیماری ها
مقاله ترجمه شده
2 Efficient biometric-based identity management on the Blockchain for smart industrial applications
مدیریت هویت مبتنی بر بیومتریک کارآمد در Blockchain برای کاربردهای صنعتی هوشمند-2021
In this work, we propose a new Blockchain-based Identity Management system for smart industry. First, we describe an efficient biometric-based anonymous credential scheme, which supports selective disclosure, suspension/thaw and revocation of credentials/entities. Our system provides non-transferability through a freshly computed hidden biometric attribute, which is generated using a secure fuzzy extractor during each authentication. This mechanism combined with offchain storage guarantees GDPR compliance, which is required for protecting user’s data. We define blinded (Brands) DLRep scheme to provide multi-show unlinkability, which is a lacking feature in Brands’ credential based systems. For larger organizations, we re-design the system by replacing the Merkle Tree with an accumulator to improve scalability. The new system enables auditing by adapting the standard Industrial IoT (IIoT) Identity Management Lifecycle to Blockchain. Finally, we show that the new proposal outperforms BASS, i.e. the most recent blockchain-based anonymous credential scheme designed for smart industry. The computational cost at the user-side (can be a weak IoT device) of our scheme is 8-times less than that of BASS. Thus, our system is more suitable for IIoT.© 2020 Elsevier B.V. All rights reserved.
Keywords: Identity management | Smart industry | Blockchain | Non-transferability | Biometrics | DLRep | Multi-show unlinkability | Selective disclosure | Accumulators
مقاله انگلیسی
3 Reconfiguration of electrical distribution network-based DG and capacitors allocations using artificial ecosystem optimizer: Practical case study
پیکربندی مجدد تخصیص DG و خازن مبتنی بر شبکه توزیع الکتریکی با استفاده از بهینه ساز اکوسیستم مصنوعی: مطالعه موردی عملی-2021
In this article, a new implementation of Artificial Ecosystem Optimizer (AEO) technique is developed for distributed generators (DGs) and capacitors allocation considering the Reconfiguration of Power Distribution Systems (RPDS). The AEO is inspired from three energy transfer mechanisms involving production, consumption, and decomposition in an ecosystem. In the production mechanism, the production operator allows AEO to produce a new individual randomly, whereas the search space exploration can be improved as illustrated in the consumption mechanism and exploitation can be performed in the decomposition. A practical case study of 59-bus Cairo distribution system in Egypt is simulated with different loading percentages. For optimizing the performance of that practical network, the AEO algorithm is employed for different scenarios. Besides, the results obtained by recent optimization techniques which are Jellyfish Search Optimizer (JFS), Supply Demand Optimizer (SDO), Crow Search Optimizer (CSO), Particle Swarm Optimization (PSO), Grey Wolf Optimizer (GWO) and Whale Optimization Algorithm (WOA) are compared with the developed AEO. The simulation results demonstrate the efficacies and superiority of the AEO compared to the others. It surpasses the other algorithms in terms of obtaining the best, mean, worst, and standard deviations. After optimal RPDS and DGs placements, the power losses are decreased by 78.4, 77.84 and 71.4% at low, nominal and high levels, respectively. However, the best scenario with its application prospects is mentioned after optimal RPDS, DGs, and capacitors where the power losses are decreased by 68.8, 85.87 and 89.91% at low, nominal and high levels, respectively.
KEYWORDS: Artificial ecosystem optimizer | Distributed generators | Electrical systems | Power losses | Reconfiguration
مقاله انگلیسی
4 Sustainability at stake during COVID-19: Exploring the role of accounting in addressing environmental crises
پایداری در معرض خطر در Covid-19: بررسی نقش حسابداری در رسیدگی به بحران های زیست محیطی-2021
In this paper, we reflect and provide insights on the environmental implications of postCOVID-19 economic recoveries. More specifically, we highlight the connection(s) between the environment and the COVID-19 crisis, in particular the intertwined links between Mother Nature and the virus. We then raise some concerns about the ‘illusionary’ positive and negative effects of the crisis on the environment before evoking some past lessons about crisis management and recovery. We contend that the current accounting and accountability mechanisms employed in economic stimulus programs, as well as traditional environmental accounting approaches, are inadequate and limiting to achieve long-term sustainability change. The paper concludes by offering accounting practitioners and researchers some possibilities to take a step forward and develop new understandings of social and environmental value consistent with ecological principles and sustainable development—and hope that these reflections will contribute to a broader debate on the role of accounting for sustainable development in the Anthropocene
keywords: بحران زیست محیطی | کووید -19 | حسابداری اجتماعی و زیست محیطی | مسئوليت | Environmental crisis | COVID-19 | Social and environmental accounting | Accountability
مقاله انگلیسی
5 NGOs, public accountability, and critical accounting education: Making data speak
سازمان‌های غیردولتی، مسئولیت‌پذیری عمومی و آموزش حسابداری انتقادی: صحبت کردن از داده‌ها-2021
The purpose of the paper is to provide theoretical and empirical insights into NGO accountability in the context of public sector accounting. We present a case study of two advocacy Italian NGOs which act as informational surrogates in the accountability relationship between local governments and the civic public. We extend the concept of surrogate accountability by integrating accounting education as one of its features. Alongside making data accessible, NGOs in our case explain accounting terms and organise educational events. By doing so, they aim to “repair” the weak information link in the accountability mechanism of local governments.
keywords: آموزش حسابداری انتقادی | پاسخگویی به سازمان های غیر دولتی | دولت باز | پاسخگویی عمومی | پاسخگویی جایگزین | شفافیت | Critical accounting education | NGO accountability | Open government | Public accountability | Surrogate accountability | Transparency
مقاله انگلیسی
6 Code as constitution: The negotiation of a uniform accounting code for U:S: railway corporations and the moral justification of stakeholder claims on wealth
کد به عنوان قانون اساسی: مذاکره در مورد یک کد حسابداری یکسان برای شرکت های راه آهن ایالات متحده و توجیه اخلاقی ادعاهای سهامداران در مورد ثروت-2021
Economic historians of the United States identify the railway industry of the nineteenth century as the birthplace of existing institutions of corporate finance, law, and labor relations (Chandler, 1990; Perrow, 2002; Thomas, 2011). This paper shows that the railway industry was also an important arena for the standardization of corporate accounting in the U. S., and that railway accountants played a significant role in the federal government’s earliest attempts to regulate large corporations. The paper describes how railway accountants worked with the first federal regulator of corporations, the Interstate Commerce Commission (ICC), created by act of Congress in 1887, to create a uniform accounting code for the railway industry. This code was designed by the prominent economist and ICC statistician Henry Carter Adams to serve as a mechanism for the administrative supervision of railway corporations: a “cognitive equivalent of a constitution” (Starr, 1987, p. 53) that would promote economic democracy by protecting the property rights of non-controlling stakeholders in the railway system: shippers who used the trains to send goods to markets, long-term investors in railway shares and bonds, consumers of shipped goods, and members of the communities that the railways connected and employed. Railway accountants working with Adams created the rules for answering “potentially divisive questions of fact” (Starr, 1987, p. 53) about who contributed how much to the assets and profits of the railway corporation, and thus provided moral justification for how claims on those assets and profits were distributed.
مقاله انگلیسی
7 Pathophysiology of Advanced Heart Failure
پاتوفیزیولوژی نارسایی پیشرفته قلب-2021
 The pathophysiologyof advanced heart failure (HF) can be characterized asa complex interplay ofdysregulated mechanisms comprising impaired hemodynamics, neurohormonal and proinflammatory activation, dysfunctional cardiorespiratory reflex control, and inadequate energy handling, all of which ultimately lead to multiorgan dysfunction; at the later stage of HF, numerous comorbidities, whose underlying pathophysiologiesoftenamplifyHFprogression,tendtodominatetheclinicalpicture and therapeutic approach, and some of these mechanisms have been identified as therapeutic targets in HF.
 Blockade of the renin-angiotensin-aldosterone system (preferably with an angiotensin receptorneprilysin inhibitor, but alternatively with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers together with mineralocorticoid receptor antagonist) and sympathetic nervous system (with b-blockers) is now considered a fundamental element of pharmacologic therapy for all patients with advanced HF and reduced ejection fraction.
 Autonomic modulation (vagal nerve stimulation or baroreflex stimulation) in advanced HF tends to benefit functional variables (qualityof life,NewYork HeartAssociation class, 6-minutewalking distance), whereas improvement in the outcomes (total mortality, HF hospitalizations) still remains uncertain.
 Fluid overload with central and/or peripheral congestion characterize the clinical picture of advanced HF and is the main reason for hospital admission in these patients; distinction of different clinical patterns of congestion with different underlying mechanisms may improve the management of fluid overload in advanced HF.
 Recent clinicaltrials have shown that the following novel therapiestargeting impairedpathophysiologic pathways in advanced HF seem to improve patients’ outcomes: (1) vericiguat, a soluble guanylate cyclase stimulator; (2) omecamtiv mecarbil, a selective cardiac myosin activator; (3) sodium-glucose cotransporter 2 inhibitors; (4) ferric carboxymaltose, for patients with concomitant iron deficiency.
 Better understanding of the pathophysiology underlying HF progression may allow characterization of novel mechanisms that can be targeted in order to revert to a natural pathway of HF development and progression.
مقاله انگلیسی
8 Pricing decisions in a decentralized biofuel supply chain with RIN mechanism considering environmental impacts
تصمیمات قیمت گذاری در زنجیره تأمین سوخت زیستی غیرمتمرکز با مکانیسم RIN با در نظر گرفتن تأثیرات زیست محیطی-2021
This study develops pricing models in a decentralized biofuel supply chain focusing on both economic and environmental aspects. Environmental impacts are used as a measure to reflect the environmental objective function calculated based on ReCiPe method. A bi-level multi-objective stackelberg game model considering farmers and biorefineries as followers and the blender as leader is proposed. An ε-constraint method is utilized to convert the multi-objective model to a single-objective one. The bi-level model is then transformed to a solvable integrated model. Finally, a real case study of switchgrass bioethanol is presented to illustrate the performance of the proposed model. Results show that focusing on environmental goals results in the increasement of selling prices and profits of farmers and biorefineries and decreasment of about %7 in economic profit of the blender. Therefore, tradeoff analyses are performed for objective functions leading to 10 Pareto optimal solutions which give managerial insights to the blender. Moreover, sensitivity analyses are provided with respects to price elasticity and final fuel’s price and results show logical trends in selling prices.
Keywords: Biofuel supply chain | Pricing | Decentralized decision making | Environmental impacts | Multi-objective optimization
مقاله انگلیسی
9 Provably secure biometric-based client–server secure communication over unreliable networks
ارتباطات امن مشتری و سرور مبتنی بر بیومتریک به طور قابل اطمینان در شبکه های غیرقابل اعتماد-2021
Due to rapid advancement in internet technologies, remote client access has become much more comfortable than in previous days. The responsibility of the system does not limit even after providing access to resources. In every system, there is a possibility that an adversary may use the resources of the system without prior authentication. This will create interruption, and the clients of the system will ultimately be affected, so the system must provide some authentication mechanism. Therefore, an authentication scheme needs to be introduced, which provides security against different attacks. Consequently, in this article, we propose a reliable and secure three factor authentication scheme that prevents various security attacks. The provable security of the proposed scheme is proved through a widely used random oracle model. We implemented the cryptographic operations of proposed and related schemes on a desktop system having good specifications to get the experimental results. Moreover, the presented scheme is compared with the existing schemes to compare its performance. The performance evaluation shows that our scheme is lightweight and efficient in terms of computation and communication costs as compared to related competing schemes.
Keywords: Anonymity | Authentication | Impersonation attack | Session key | Smartcard
مقاله انگلیسی
10 Digital extraction: Blockchain traceability in mineral supply chains
استخراج دیجیتال: قابلیت ردیابی بلاکچین در زنجیره های تأمین مواد معدنی-2021
Digital data — including technologically-mediated data generated by blockchain-enabled traceability — is performing an increasingly integral role in extractive operations, but scarce attention has been paid to the structuring effect of these digital technologies or the socio-economic spatiality of data-driven mining operations. Drawing on extensive qualitative research (interviews, participant observation, and two sets of survey data among actors relevant to these mineral supply chains), this article advances the notion of “digital extraction” todescribe the collection, analysis, and instrumentalization of digital data generated under the banner of blockchain-based due diligence, chain of custody certifications, and various transparency mechanisms, situated alongside and in support of mineral extraction. The article mobilizes concepts from political geography and political ecology to argue that digital technologies of traceability in extractive processes potentially create new forms of control and exclusion or exacerbate existing social, political, and territorial dispossession through asymmetric relations of power and knowledge in mineral supply chains. Despite industry efforts to make mineral supply chains more sustainable by resorting to digital certification and traceability, the strategic uses of un- certainty, ignorance, and ambiguity undergirding blockchain-enabled traceability systems fail to challenge existing inequalities in resource use and access or fulfill the promise of transparency and accountability.
Keywords: Blockchain | Traceability | Mining | Digital extraction | Certification | Digital technology | Political ecology
مقاله انگلیسی
rss مقالات ترجمه شده rss مقالات انگلیسی rss کتاب های انگلیسی rss مقالات آموزشی
logo-samandehi