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A Prenatal Ultrasound Scanning Approach: One-Touch Technique in Second and Third Trimesters
رویکرد اسکن سونوگرافی قبل از تولد: تکنیک یک لمس در سه ماهه دوم و سوم-2021 This study was aimed at evaluating the performance of the innovative technique Smart Fetus (SF) developed to recognize the planes and obtain the basic biometric measurements of fetuses automatically. This prospective study included 1005 uncomplicated singleton pregnancies undergoing routine examinations. For every
pregnancy, planes, including the transverse section of the thalami, transverse section of the abdomen and longitudinal section of the femur, were acquired, and standard biometric measurements, including biparietal diameter,
head circumference, abdominal circumference and femur length, were obtained using SF and traditional ultrasound technique (TUT). The accuracy, reproducibility and time required for the analysis of SF were compared
with those of TUT. In 998 of 1005 cases (99.30%), SF successfully acquired the sections and made all measurements.
The agreement between the techniques was high for all measurements. The time to obtain sections and measure biometric parameters or solely measure biometric parameters was significantly shorter with SF than with TUT. No
significant differences were found in SF repeated measurements obtained by two independent observers. The SF
technique helped in the acquisition of reliable standard sections and biometric measurements and saved time. It
might serve as a novel ultrasound scanning approach and improve workflow efficiency. (E-mail: lishengli63@126.
com) © 2021 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
KeyWords: Artificial intelligence | Biometric measurement | Fetus | Prenatal ultrasonography | Standard plane. |
مقاله انگلیسی |
2 |
Association Between Abnormal Fetal Head Growth and Autism Spectrum Disorder
ارتباط بین رشد غیرطبیعی سر جنین و اختلال طیف اوتیسم-2021 Objective: Despite evidence for the prenatal onset of abnormal head growth in children with autism spectrum disorder (ASD), studies on fetal
ultrasound data in ASD are limited and controversial.
Method: We conducted a longitudinal matched case-siblingcontrol study on prenatal ultrasound biometric measures of children with ASD, and 2 control groups: (1) their own typically developed sibling (TDS) and (2) typically developed population (TDP). The cohort comprised 528 children (72.7% male), 174 with ASD, 178 TDS, and 176 TDP. Results: During the second trimester, ASD and TDS fetuses had significantly smaller biparietal diameter (BPD) than TDP fetuses (adjusted odds ratio for the z score of BPD [aORzBPD] ¼ 0.685, 95% CI ¼ 0.5270.890, and aORzBPD ¼ 0.587, 95% CI ¼ 0.4590.751, respectively). However, these differences became statistically indistinguishable in the third trimester. Interestingly, head biometric measures varied by sex, with male fetuses having larger heads than female fetuses within and across groups. A linear mixed-effect model assessing the effects of sex and group assignment on fetal longitudinal head growth indicated faster BPD growth in TDS versus both ASD and TDP in male fetuses (b ¼ 0.084 and b ¼ 0.100 respectively; p < .001) but not in female fetuses, suggesting an ASD–sex interaction in head growth during gestation. Finally, fetal head growth showed conflicting correlations with ASD severity in male and female children across different gestation periods, thus further supporting the sex effect on the association between fetal head growth and ASD. Conclusion: Our findings suggest that abnormal fetal head growth is a familial trait of ASD, which is modulated by sex and is associated with the severity of the disorder. Thus, it could serve as an early biomarker for ASD. Key words: autism spectrum disorder | prenatal ultrasound | head growth | fetal development |
مقاله انگلیسی |