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Physicians knowledge and practice concerning diagnosis and management of anaphylaxis: The situation in Egypt
دانش و عمل پزشکان در مورد تشخیص و مدیریت آنافیلاکسی: وضعیت در مصر-2021 Introduction: Early recognition of an anaphylaxis event is crucial for instituting lifesaving management. We
sought to explore knowledge and practice towards anaphylaxis in a sample of physicians from ten Egyptian
governorates.
Methods: An eighteen question-based questionnaire was developed by expert allergists to evaluate the knowledge and practice towards anaphylaxis, based on the World Allergy Organization guidelines for the assessment and management of anaphylaxis. The questionnaires were distributed, and the answered forms collected via emails, and data were tabulated, and analysed. Results: In this cross-sectional study, a total of 242 physicians completed the survey (183 (75.6%) paediatricians, 32 (13.2%) internists, 22 (9.1%) intensivists and five (2.1%) anaesthetists). Only 91 participants (37.6%) identified all the four proposed anaphylaxis clinical scenarios while 70, 45 and 36 identified three, two and one scenario, respectively. Loss of consciousness and abdominal symptoms were not recognised as possible presentations of anaphylaxis by 64.5% and 80.2% of the participants, respectively. Epinephrine was considered the first line treatment by 98 (40.5%), corticosteroids by 77 (31.8%) and antihistamines by 25 (10.3%). 75 (31%) responders identified the right dose of epinephrine while 119 (49.2%) identified the proper route. Concerning practice, 83 physicians (39.2%) used epinephrine for all cases of anaphylaxis, 88 (41.5%) used it for refractory cases only whereas 41 (19.3%) did not use epinephrine at all. Discussion: Our survey shows that the knowledge of Egyptian physicians and their practice towards anaphylaxis are still inadequate. The current situation reinforces the need to disseminate and encourage the adoption of the international guidelines for anaphylaxis diagnosis and treatment. keywords: آنافیلاکسی | اپینفرین | واکنش های آلرژیک کشنده | دانش | تمرین | Anaphylaxis | Epinephrine | Fatal allergic reactions | Knowledge | Practice |
مقاله انگلیسی |
2 |
Food allergomics based on high-throughput and bioinformatics technologies
آلرژیک مواد غذایی بر اساس فن آوری های توان بالا و بیوانفورماتیک-2020 Food allergy is a serious food safety problem worldwide, and the investigation of food allergens is the foundation
of preventing and treating them, but relevant knowledge is far from sufficient. With the advent of the “big data
era”, it has been possible to investigate food allergens by high-throughput methods, proposing the concept of
allergomics. Allergomics is the discipline studying the repertoire of allergens, which has relatively higher
throughput and is faster and more sensitive than conventional methods. This review introduces the basis of
allergomics and summarizes its major strategies and applications. Particularly, strategies based on immunoblotting,
phage display, allergen microarray, and bioinformatics are reviewed in detail, and the advantages
and limitations of each strategy are discussed. Finally, further development of allergomics is predicted. This
provides basic theories and recent advances in food allergomics research, which could be insightful for both food
allergy research and practical applications. Keywords: High-throughput | Bioinformatics | Allergome | Allergomics | Food allergy |
مقاله انگلیسی |
3 |
Nannies’ Knowledge, Attitude, and Management o f Food Allergies of Children: An Online Survey
آگاهی، نگرش، و مدیریت دایه-2015 BACKGROUND: Rates of food allergies in children as well as
the rate of families who employ nannies have increased
dramatically over the past decade. It is essential that nannies
have the knowledge and tools necessary to recognize and treat
food allergy reactions.
OBJECTIVE: To identify gaps in knowledge in the nanny
population with regard to food allergy in children.
METHODS: A Web-based survey was sent by e-mail to 709 nannies.
RESULTS: A total of 153 nannies (22%) completed the online
survey: 26% of respondents had formal educational training at a
nanny school; 99% recognized food allergy as a potentially fatal
event; 37% reported caring for a child with food allergies. Of
these, 71% had food allergy action plans, and 63% had
epinephrine available. A total of 71% reported training on
administering epinephrine. The nannies’ major concerns
included accidental ingestion and discomfort in administering
epinephrine. A total of 36% were uncomfortable with
recognizing a food allergy emergency, whereas 46% were
uncomfortable administering epinephrine; 6% thought that a
sensitized child could safely eat a small amount of allergenic
food, whereas 14% believed that dilution with water might
reduce an allergic reaction. A total of 66% desired additional
information about recognizing food allergies, and 71% agreed
that food allergy training should be required for all nannies.
CONCLUSION: Nannies demonstrated gaps in knowledge with
regard to food allergy in children, which refl ects the need for
more stringent training and education. Increased
communication among parents, nannies, and physicians is
needed to protect children with food allergy
Key words:Key words: Food allergy; Nanny; Children; Child care;
Epinephrine; Survey |
مقاله انگلیسی |